According to ESPN’s Adam Schefter, the 49ers will be playing the Arizona Cardinals on November 21st, 2022, at the Estadio Azteca in Mexico City, which will be a Monday Night Game on ESPN at 8PM EST/5PM PST.
The remainder of the NFL schedule will be released next Thursday, May 12th, on both ESPN, & NFL Network.
49ers will play the Cardinals at Estadio Azteca in Mexico City on Nov 21.
— Adam Schefter (@AdamSchefter) May 4, 2022
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